Custom Peptides
Cayman Chemical BB22 3carboxyIndl metaol 10mg
An expected metabolite of BB-22 that would be detectable both in serum and urine; intended for forensic and research applications
Cayman Chemical NorverapamIlhydrochlorIde 10mg
The major active metabolite of the L-type calcium channel blocker verapamil; inhibits mycobacterial efflux pumps and the expansion of M. tuberculosis-specific T cells
Cayman Chemical 8-HydroxygunInhydrochlorI 10mg
An internal standard for the quantification of MDMB-BUTINACA by GC- or LC-MS intended for research and forensic applications
Cayman Chemical 2OAcetyl20hydroxyecdyson 10mg
An ecdysone steroid hormone; completely inhibits the growth of the bacteria S. aureus, E. coli, and P. vulgaris, as well as the fungi C. albicans, A. alternata, and F. solani at 10 UG/ml; increases aggregation of Aβ42, increases fibril formation by 60%, and decreases oligomer levels in cell-free assays at 50 µM; reduces Aβ42-induced cytotoxicity of SH-SY5Y cells at 5 and 10 µM
Cayman Chemical Fz721trIfluoroACTAte salt 10mg
A peptide antagonist of the FZD7 receptor (IC50 = 100 nM); inhibits Wnt3a-induced β-catenin signaling in a reporter assay using HEK293 cells; reduces the number of Lrg5-positive cells and the mRNA encoding Ash-2 and Axin2 and increases mRNA encoding Muc2 in primary mouse intestinal organoids at 100 µM
Cayman Chemical GnoderIc AcId G 10mg
A triterpenoid with anticancer and anti-inflammatory activities; inhibits proliferation of Meth A sarcoma cells (IC50 = 6.8 UG/ml); inhibits the production of NO in LPS-induced BV-2 microglial cells (IC50 = 5.77 µM)
Cayman Chemical Soyaspogenol B 10mg
A triterpenoid with diverse biological activities; inhibits LPS-induced increases in the levels of NO in RAW 264.7 macrophages at 95.6 µM; decreases triglyceride levels, as well as increases glycerol and free fatty acids levels in, and decreases the levels of resistin secreted from, 3T3-L1 adipocytes at 12.5 µM; reduces plasma levels of ALT in a mouse model of concanavalin A-induced autoimmune hepatitis
Cayman Chemical N- 3-AmInopropylacetamIde 10mg
A monoacetylated polyamine that can be used as a building block in the synthesis of heterocyclic compounds
Cayman Chemical RhodIola rosea RosarIn 10mg
A glycoside with anti-inflammatory and immune regulatory activities; prevents LPS-induced increases in iNOS, TNF-α, IL-1β, and IL-6 levels in BV-2 microglia at 10 and 50 UG/ml; inhibits concanavalin A- or anti-CD3 and anti-CD28 antibody-induced growth of Jurkat T cells (IC50s = 60 and 68 µM, respectively); increases TRAIL levels in isolated mouse splenic T cells
Cayman Chemical NorfluoxetInhydrochlorIde 10mg
An active metabolite of fluoxetine; inhibits 5-HT uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM); has been found in the tissues of fish exposed to wastewater effluent
Cayman Chemical PPACKhydrochlorIde 10mg
A synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM); used as an anticoagulant (100 μM)
Cayman Chemical PhosphatIdylethnolamInsoy 10mg
A mixture of phosphatidylethanolamines isolated from soy; comprises approximately 25% of total mammalian phospholipids and almost 50% of brain phospholipids; found mainly in the cell membrane; synthesized mainly in the ER and mitochondrial membranes; acts as a chaperone in E. coli for lactose permease assembly; cofactor for prion propagation that can convert recombinant mammalian proteins into infectious molecules
Cayman Chemical 1Stearoyl2PalmItoylracgl 10mg
A diacylglycerol containing stearic acid and palmitic acid; has been used to delay drug release in a hydrophilic medium
Cayman Chemical nastrozole 10mg
An aromatase/CYP19A1 inhibitor (IC50 = 15 nM for human placental aromatase/CYP19A1); selective for aromatase/CYP19A1 over CYP1A2, CYP2A6, CYP2C9, CYP2D6, and CYP3A (IC50s = 27-650 μM); blocks ovulation in mature female rats and androstenedione-stimulated uterine development in pubertal female rats at 0.1 mg/kg; inhibits peripheral aromatase/CYP19A1 and reduces plasma estradiol concentrations in male pigtailed monkeys at ≥0.1 mg/kg; reduces tumor incidence and the number of tumors well as increases latency to tumor appearance in a rat model of premenopausal mammary tumorigenesis at 0.5 mg/kg
Cayman Chemical FluphenazIn decnoate 10mg
A prodrug form of fluphenazine; induces random mouth movements in rats; increases serum levels of prolactin and decreases LH and FSH, as well as decreases desire to mate and litter size, in male rats at 3 mg/kg per day; It increases lethargy and passive contact and reduces self-grooming, social grooming, auditory startle response, and propensity to attack other animals in monkeys